Fig. 3

Multivariable logistic regression analysis assessing the value of cut-off scores for predicting flare. Analysis was performed for flare status at WD+6mo and WD+12mo. A multivariable logistic regression model, adjusted for treatment arm, determined whether patient-reported outcome (PRO) and MRI measures at WD were independent predictors of flare at WD+6mo and WD+12mo. P values in bold type indicate statistical significance. Vertical line indicates limit of effect: positive data indicate effect, negative data or data that cross 1 indicate absence of effect. *Synovitis score + (2x bone edema score). MTX methotrexate, SC subcutaneous. See Fig. 1 for other definitions