Table 2 Safety cohort histopathological scoring for each group at day 21
Vehicle control | 50 μL ASA | |
|---|---|---|
Total joint score | 0.35 ± 0.11 | 0.40 ± 0.10 |
Total joint score minus femur | 0.35 ± 0.11 | 0.40 ± 0.10 |
Cartilage degeneration width (μm)a | 10.00 ± 10.00 | 6.00 ± 6.00 |
Bone damage score | 0.00 ± 0.00 | 0.00 ± 0.00 |
Bone sclerosis score | 0.20 ± 0.13 | 0.20 ± 0.13 |
Osteophyte score | 0.00 ± 0.00 | 0.00 ± 0.00 |
Osteophyte measurement (μm) | 0.00 ± 0.00 | 0.00 ± 0.00 |
Synovitis | 0.20 ± 0.08 | 1.15 ± 0.21** |