Table 4 MMT cohort histopathological scoring for each group at day 21

Total joint score

0.20 ± 0.12‡

11.50 ± 0.82

10.07 ± 0.48

9.87 ± 0.26

Total joint score minus femur

0.20 ± 0.12‡

9.93 ± 0.68

8.85 ± 0.33

8.10 ± 0.23*

Cartilage degeneration width (μm)^a

0.00 ± 0.00‡

670.00 ± 60.18

590.00 ± 36.28

245.00 ± 34.88‡

Bone damage score

0.00 ± 0.00‡

1.73 ± 0.13

1.87 ± 0.28

2.83 ± 0.24^

Bone sclerosis score

0.20 ± 0.20‡

2.40 ± 0.16

2.47 ± 0.09

2.33 ± 0.22

Osteophyte score

0.00 ± 0.00‡

4.00 ± 0.25

3.57 ± 0.34

5.00 ± 0.00^

Osteophyte measurement (μm)

0.00 ± 0.00‡

525.00 ± 24.50

483.33 ± 30.83

988.33 ± 47.27‡

Synovitis

0.00 ± 0.00‡

0.53 ± 0.05

0.92 ± 0.14

3.80 ± 0.13‡