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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritis

Fig. 5

Expression spectrum of G3BP in kidneys of 24 patients with lupus nephritis. a Clusters of kidney cells identified with public scRNA-seq data. Cluster annotations: CM0, CD16+ machrophage, inflammatory; CM1, CD16+ macrophage, phagocytic; CM2, tissue-resident macrophage; CM3, cDCs; CM4, CD16+ macrophage, M2-like; CT0a, effector memory CD4+ T cells; CT0b, central memory CD4+ T cells; CT1, CD56_dim CD16+ NK cells; CT2, CTLs; CT3a, Tregs; CT3b, TFH-like cells; CT4, GZMK+ CD8+ T cells; CT5a, resident memory CD8+ T cells; CT5b, CD56_bright CD16- NK cells; CT6, ISG-high CD4+ T cells; CB0, activated B cells; CB1, plasma cells/plasmablasts; CB2a, naive B cells; CB2b, pDCs; CB3, ISG-high B cells; CD0, dividing cells; CE0, epithelial cells. b, c Expression of G3BP on kidney cells (https://singlecell.broadinstitute.org/single_cell/study/SCP279/amp-phase-1#study-visualize, accessed on Feb. 25, 2022)

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Arthritis Research & Therapy

ISSN: 1478-6362

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