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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Lupus nephritis correlates with B cell interferon-β, anti-Smith, and anti-DNA: a retrospective study

Fig. 4

Association of B cell IFNβ with the location of immune complexes in renal biopsy. Renal biopsies were obtained from 23 available specimens. The immune complexes were scored based on the presence each indicated type in the glomerular basement membrane (A), mesangium (B), renal tubular (C), and arterioles/arteries (D) using a 0 to 4 scoring range: 0, absent, 1 rare, 2 low abundance, 3 moderate abundance, and 4 high abundance. LN patients were divided into two groups based on the levels of B cell IFNβ either below the mean (IFNβ low, n = 10) or above the mean (IFNβ high, n = 13) (data are mean ± SEM; 2-way ANOVA test on the effects of B cell IFNβ and IC type in each region)

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