Table 3 Incidence rate per 100 patient-years and incidence rate ratio of hospitalized infection
Young (14,668.59 PY) | Elderly (10,611.63 PY) | Older elderly (7,911.10 PY) | |
|---|---|---|---|
Number of HIs | 473 | 534 | 804 |
Overall IR [95% CI] | 3.20 [2.92–3.50] | 4.99 [4.58–5.43] | 10.14 [9.45–10.85] |
IRR [95% CI] (vs. young) | Reference | 1.56 [1.38–1.77] | 3.17 [2.83–3.55] |
IR [95% CI] during exposure to MTX | 2.34 [2.03–2.69] | 4.90 [4.39–5.46] | 11.0 [10.1–12.0] |
IR [95% CI] during exposure to bDMARDs/JAKIs | 4.33 [3.84–4.87] | 5.12 [4.47–5.86] | 8.74 [7.75-–9.82] |
IRR [95% CI] (bDMARDs/JAKIs vs. MTX) | 1.85 [1.54–2.22] | 1.05 [0.88–1.24] | 0.79 [0.68–0.92] |