Fig. 5
From: Dark-light cycle disrupts bone metabolism and suppresses joint deterioration in osteoarthritic rats
Changes in expression of clock proteins in representative tissues. A Expression of BMAL1, NR1D1, CRY1, and PER3 protein in heart, liver, spleen, lung, and kidney of OA rats via WB. Unpaired two-tailed Student’s t test or with Welch’s correction, or using the Mann-Whitney test: n = 3 per group. B Expression of BMAL1 protein of tibial cartilage, synovium, and bone marrow of OA rats via IHC staining. Scale bar, 50 μm. n = 3 per group