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Table 5 Minimum detectable difference for each echocardiographic measure of right ventricular function

From: Defining minimal detectable difference in echocardiographic measures of right ventricular function in systemic sclerosis

Parameter Minimal detectable difference
Total SSc population Cohort 1 (SSc without PAH) Cohort 2 (SSc with PAH)
TAPSE, cm 0.1 0.1 0.2
FAC, % 2.9 4.0 5.0
S’ wave, cm/s 1.3 0.8 1.0
RVOT VTI, cm 0.8 1.2 0.8
Global RVLSS, % 1.1 1.8 1.3
RVSP, mmHg 6.5 2.2 6.3
TAPSE to PASP, mm/mmHg 0.1 0.16 0.11
  1. Abbreviations: TAPSE tricuspid annular plane systolic excursion, FAC fractional area change, S’ tissue Doppler-derived right ventricular systolic excursion velocity, RVOT right ventricular outflow tract, VTI velocity time integral, RVLSS right ventricular longitudinal systolic strain, RVSP right ventricular systolic pressure, PASP pulmonary artery systolic pressure