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Table 2 Adjusted hazard ratios and 95% CI for myocardial infarction and stroke in RA cohorts, comparing SSDI beneficiaries to Marketscan enrollees

From: Comparing cardiovascular risk of patients with rheumatoid arthritis within the Social Security Disability Insurance with those commercially insured

Cohort Outcome Adjusted HR model 1
(95% confidence interval)a
Adjusted HR model 2
(95% confidence interval)b
Adjusted HR model 3
(95% confidence interval)c
Cohort 1 MI 1.99 (1.85–2.15) 1.40 (1.30–1.50) 1.46 (1.33–1.60)
Stroke 1.29 (1.18–1.41) 1.00 (0.92–1.09) 0.92 (0.82–1.03)
MI or stroke 1.65 (1.56–1.75) 1.20 (1.14–1.27) 1.20 (1.12–1.29)
Cohort 2 MI 1.99 (1.83–2.15) 1.42 (1.32–1.54) 1.49 (1.35–1.65)
Stroke 1.24 (1.12–1.36) 0.99 (0.91–1.08) 0.92(0.82–1.04)
MI or stroke 1.63 (1.53–1.74) 1.21 (1.15–1.29) 1.23 (1.14–1.33)
Cohort 3 MI 1.42 (1.10–1.83) 0.92 (0.73–1.16) 1.03 (0.75–1.42)
Stroke 1.28 (0.95–1.72) 0.87 (0.66–1.15) 0.85 (0.58–1.24)
MI or stroke 1.33 (1.09–1.61) 0.87 (0.73–1.04) 0.89 (0.69–1.15)
  1. SSDI Social Security Disability Insurance
  2. aAdjusted for age and sex
  3. bAdjusted for variable included in model 1 and other CVD risk, and obesity. Other CVD risk was defined as baseline CCS 101 (coronary atherosclerosis and other heart disease), CCS108 (congestive heart failure; non-hypertensive), CCS127 (chronic obstructive pulmonary disease and bronchiectasis), CCS206 (spondylosis; intervertebral disc disorders; other back problems), CCS244 (other injuries and conditions due to external causes), CCS257 (other aftercare), CCS4 (mycoses), CCS49/50 (diabetes mellitus with or without complication), CCS55 (fluid and electrolyte disorders), CCS663 (screening and history of mental health and substance abuse codes), CCS98/99 (essential hypertension or hypertension with complications and secondary hypertension), number of physician visit in baseline, smoking, IP hospitalized during baseline (1/0), and use other anti-diabetes drugs during baseline
  4. cAdjusted for variable included in model 2 and dual eligible (Medicare and Medicaid beneficiary), subsidy, and state buy in