Table 2 Demographic characteristics of study populations in active disease
Diagnosis | GPA | MPA | TAK | GCA |
|---|---|---|---|---|
Number of subjects | 73 | 11 | 8 | 18 |
Gender (female, %) | 38 (52%) | 6 (55%) | 8 (100%) | 12 (67%) |
Age at diagnosis, years (median, range) | 47 (10–80) | 67 (28–75) | 28 (14–44) | 69 (58–83) |
Disease duration (mean ± SD, years) | 6.8 ± 7.6 | 4.0 ± 5.2 | 6.9 ± 4.1 | 1.6 ± 1.8 |
ESR (mean ± SD, mm/h) | 17.2 ± 13.9 | 31.1 ± 37.3 | 27.7 ± 22.3 | 16.2 ± 18.6 |
CRP (mean ± SD, mg/dl) | 11.7 ± 22.7 | 17.2 ± 39.1 | 11.6 ± 13.3 | 11.7 ± 18.3 |
Creatinine (mean ± SD, mg/dl) | 1.12 ± 0.77 | 1.98 ± 1.12 | 0.76 ± 0.13 | 0.92 ± 0.23 |
Anti-MPO antibodies (%) | 6 (8%) | 11 (100%) | ND | ND |
Anti-PR3 antibodies (%) | 55 (75%) | 0 (0%) | ND | ND |
PGA (mean ± SD) | 3.30 ± 1.73 | 4.09 ± 1.92 | 3.88 ± 1.46 | 2.78 ± 1.22 |