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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: The potential roles of type I interferon activated neutrophils and neutrophil extracellular traps (NETs) in the pathogenesis of primary Sjögren’s syndrome

Fig. 2

RNA-seq analysis for pSS neutrophils (pSS=7, HC=6). A The volcano plot for DE mRNAs of pSS neutrophils (239 upregulated in red and 181 downregulated mRNAs in blue, TOP 5 up- and downregulated genes were annotated). B The hierarchical clustering heatmap for DE mRNAs of the pSS neutrophils. C GO enrichment analysis for DE mRNAs of pSS neutrophils (implemented by the clusterProfiler R package). D GSEA for the potential function of DE mRNAs of pSS neutrophils. E KEGG analysis for the potential pathways of pSS neutrophils’ DE mRNAs. Different colors represented for the different signaling pathways. *P-value < 0.05, **P-value < 0.01, ***P-value <0.001)

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Arthritis Research & Therapy

ISSN: 1478-6362

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