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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Factors secreted by monosodium urate crystal-stimulated macrophages promote a proinflammatory state in osteoblasts: a potential indirect mechanism of bone erosion in gout

Fig. 4

Secretion of proinflammatory mediators from THP-1 monocytes stimulated with MSU crystals. THP-1 monocytes were cultured with MSU crystals for 20 h for preparation of MSU crystal-stimulated and control conditioned media. Concentrations of proinflammatory mediators were determined by ELISA. Means (SEM) of data pooled from three biological repeats are presented. Data were analyzed by one-way ANOVA with post hoc Dunnett’s test. *p < 0.05 and **p < 0.01, versus control without MSU crystals

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Arthritis Research & Therapy

ISSN: 1478-6362

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