Fig. 1

Mean pain intensity scores stratified by disease activity categories at 12 months. Mean scores are represented by the black dots, and 95% confidence intervals by vertical black bars. Each patient’s pain VAS score is plotted as grey points, with “jitter” applied across the horizontal axis to prevent overplotting; early = early active RA trials; established = established active RA trials; remission/LDA = remission/LDA studies; REM = remission; LDA = low disease activity; MDA = moderate disease activity; HDA = high disease activity