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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype

Fig. 2

FLS are heterogeneous. Workflow diagram for initial data input and processing to provide a summary of how data was processed (A). Heatmaps reveal the 30 top variable genes that have the greatest differential expression within single cells (B). Of the 30 genes, there were 16 unique differentially expressed genes within cells from oligo, 22 unique differentially expressed genes within cells from ETB, and 15 unique differentially expressed genes within cells from poly (C). There were 4 genes that overlapped between oligo and ETB, 11 genes that overlapped between oligo and poly, and 6 genes that overlapped between ETB and poly (C). These genes can be used to differentiate between JIA subtypes

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