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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study

Fig. 4

The rates of gout and asymptomatic hyperuricemia (AH) compared to those with normouricemia among different quartile polygenic risk scores (PRS). The rates of gout and AH increased with increased quartile PRS in those variants with risk effects (odds ratio (OR) >=1; red color) of developing the phenotypes (A, B, respectively). Whereas the rates of gout and AH decreased with increased quartile PRS in those variants with protective effects (OR <1; blue color) of developing the phenotypes (C, D, respectively). The rates of gout/AH were calculated only in the participants for estimating PRS, but not in the whole population. HUA, hyperuricemia

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Arthritis Research & Therapy

ISSN: 1478-6362

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