Skip to main content

Table 2 Markers of endothelial dysfunction in early and long-standing MTX-treated RA patients

From: Methotrexate improves endothelial function in early rheumatoid arthritis patients after 3 months of treatment

 

MTX at 3 months,

N = 14

Long-standing MTX treatment,

N = 15

p

Tang (%)

22.9 ± 10.6

23.7 ± 6.0

0.533

CD28 + Tang (%)

48.4 ± 14.6

36.2 ± 9.2

0.146

CD28nullTang (%)

51.6 ± 14.6

63.8 ± 18.1

0.146

EMPs (n/µl)

377 ± 468

281 ± 155

0.919

Platelet CD40L (%)

6.9 ± 1.1

9.9 ± 1.9

0.201

EPCs (n/µl)

4.7 ± 2.5

6.7 ± 4.4

0.482

CECs (n/µl)

10.2 ± 2.3

14.9 ± 7.6

0.892

  1. Markers of endothelial and platelet function do not significantly differ between RA patients treated with methotrexate for 3 months and patients with long-term treatment. Data are shown as mean ± standard error