Skip to main content
Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Augmented PFKFB3-mediated glycolysis by interferon-γ promotes inflammatory M1 polarization through the JAK2/STAT1 pathway in local vascular inflammation in Takayasu arteritis

Fig. 1

Expression and co-localization of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) and interferon (IFN)-γ in macrophages of the adventitia in Takayasu arteritis (TAK). A, B Expression of IFN-γ and PFKFB3 in the aortic adventitia (n = 12 for TAK, n = 8 for control); C, D expression of IFN-γ, CD68, and PFKFB3 in TAK adventitia (n = 9 for TAK; n = 6 for control); E the Spearman correlation analysis of the expression (MFI) between IFN-γ and PFKFB3. MFI mean fluorescence intensity. Data revealed as mean ± SEM; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us