Fig. 3

Histological studies of femurs from ovariectomized mice show a reduction in osteoclast number and an increase in osteoblast number and bone formation. a–d Representative images and quantification of TRAP staining of mice femur (in pink). b–e Representative images and quantification of ALP staining of mice femur (in brown). c–f Representative images and quantification of dynamic bone histomorphometry after double labeling with Alizarin Red and calcein. *p<0.05 vs Control, #p<0.05 vs Saline, & p<0.05 vs AlenP