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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Novel alendronate-CGS21680 conjugate reduces bone resorption and induces new bone formation in post-menopausal osteoporosis and inflammatory osteolysis mouse models

Fig. 4

Ī¼CT studies of wear particle-induced osteolysis show how MRS7216 is effective at reducing bone pitting in WT mice but not in A2A KO mice. a Representative images of mice calvaria. b Quantification of the damaged bone area in WT mice calvaria. c BMD quantification in WT mice calvaria. d Quantification of the damaged bone area in A2A KO mice calvaria. e BMD quantification in A2A KO mice calvaria. * p<0.05 vs saline, & p<0.05 vs AlenP

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