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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: circ-Iqsec1 induces bone marrow-derived mesenchymal stem cell (BMSC) osteogenic differentiation through the miR-187-3p/Satb2 signaling pathway

Fig. 3

Downregulation of circ-Iqsec1 significantly decreases BMSC osteogenic differentiation ability. A RT-qPCR data showing circ-Iqsec1 expression in BMSCs after siRNA transfection against circ-Iqsec1 or NC. Outcomes are expressed as the mean ± SD. B, C RT-qPCR data showing RUXN2 and OCN expression after osteogenic induction for 3 weeks. Outcomes are represented as the mean ± SD. D, E Immunohistochemical staining for ALP and alizarin red staining for calcium showing BMSC osteogenic differentiation ability post silencing circ-Iqsec1. ***P < 0.001 vs. NC

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Arthritis Research & Therapy

ISSN: 1478-6362

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