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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: circ-Iqsec1 induces bone marrow-derived mesenchymal stem cell (BMSC) osteogenic differentiation through the miR-187-3p/Satb2 signaling pathway

Fig. 6

miR-187-3p downregulation or Satb2 overexpression restored BMSC osteogenic differentiation ability after silencing circ-Iqsec1. A, B RT-qPCR data showing RUNX2 (A) and OCN (B) expression. Results are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 vs. NC. ##P < 0.01, ###P < 0.001 vs. si-circ-Iqsec1. C, D Immunohistochemical staining for ALP and alizarin red staining for calcium showing BMSC osteogenic differentiation ability

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Arthritis Research & Therapy

ISSN: 1478-6362

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