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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: circ-Iqsec1 induces bone marrow-derived mesenchymal stem cell (BMSC) osteogenic differentiation through the miR-187-3p/Satb2 signaling pathway

Fig. 7

Upregulation of Satb2 restored the osteogenic differentiation ability of BMSCs after overexpression of miR-187-3p. A, B RT-qPCR detection shows the expression of miR-187-3p and Satb2. Data are expressed as the mean ± SD. **P < 0.01, ***P < 0.001 vs NC. ###P < 0.001 vs mimic. C, D RT-qPCR detection shows the expression of RUNX2 (A) and OCN (B). Data are expressed as the mean ± SD. *P < 0.05, ***P < 0.001 vs NC###P < 0.001 vs mimic. E, F Immunohistochemical staining for ALP and alizarin red staining show the osteogenic differentiation ability of BMSCs

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