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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Early removal of the infrapatellar fat pad/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs

Fig. 1

Mobility assessments. (A) Schematic of treadmill-based gait analysis measurements. (B) Video still image showing a guinea pig running on a transparent treadmill (viewed from below) at 45 cm/s. Placement for each paw is detected from the video illustrated in A. (C) Paw area in contact with treadmill surface over time for a representative single paw (left hind limb), from which multiple stride indices can be obtained (labeled). Longitudinal data of IFP (blue) and replacement tissue (red) contralateral limb measurements of midline distance (D), stride length (E), swing (F), stance (G), brake (H), and propel time (I). Voluntary weight-bearing assessments between fore/hind symmetry (J), maximum force (K), and stride velocity (L). P-values represent the significance of two-way ANOVA (or mixed model) with Tukey’s post hoc test analyses

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Arthritis Research & Therapy

ISSN: 1478-6362

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