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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement

Fig. 1

Collagen treatment successfully induced RA, and NAR treatment alleviated the degree of arthritic score and pain in CIA rats. A Experimental design and treatment strategies. B Arthritic score in CIA rats. C CIA rats toe volume. D Mechanical pain threshold in CIA rats. E Thermal withdrawal latency in CIA rats. *P < 0.05 vs. naive group, **P < 0.01 vs. naive group. #P < 0.05 vs. CIA model group, ##P < 0.01 vs. CIA model group, by repeated-measures two-way ANOVA followed by post hoc Dunnett’s multiple comparisons test (Rats from PID0 to PID21 are n = 12/group. From PID28 to PID35 are n = 6/group). PID: days post the second immunization. In this and subsequent figures, the experimenters were blinded to the treatment condition(s)

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Arthritis Research & Therapy

ISSN: 1478-6362

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