Achilles enthesitis on physical examination leads to worse outcomes after 2 years of follow up in patients with ankylosing spondylitis from REGISPONSER-AS registry

Table 3 Impact of the presence of Achilles enthesitis on patient-reported outcomes over two years of follow-up: mixed models for repeated measures

	Current Achilles enthesitis N = 46	No current Achilles enthesitis N = 703	Crude p-value	p-value adjusted*
Global VAS, mean (SD)	5.1 (2.8)	4.3 (2.6)	0.015	0.008
BASDAI, mean (SD)	4.8 (2.7)	3.9 (2.7)	< 0.001	< 0.001
mBASDAI, mean (SD)	5.2 (2.5)	4.5 (2.3)	< 0.001	0.005
ASDAS, mean (SD)	2.9 (1.1)	2.6 (1.0)	0.007	0.001
BASFI, mean (SD)	43.8 (29.7)	40.0 (27.4)	0.245	0.119
PC-SF12, mean (SD)	33.3 (11.4)	35.3 (10.7)	0.128	0.064
MC-SF12, mean (SD)	47.4 (14.2)	48.2 (12.2)	0.547	0.399

MMRM mixed model for repeated measures
^*Adjusted for age, body mass index and current anti-TNF
ASDAS-CRP Ankylosing Spondylitis Disease Activity Score, BASDAI, Bath Ankylosing Spondylitis Disease Activity Index, BASFI Bath Ankylosing Spondylitis Functional Index, Global VAS, patient’s global visual analog scale, mBASDAI modified Bath Ankylosing Spondylitis Disease Activity Index, MC-SF12 mental component from the SF-12 questionnaire, PC-SF12 physical component from the SF-12 questionnaire

ISSN: 1478-6362