Proteomic aptamer analysis reveals serum markers that characterize preclinical systemic sclerosis (SSc) patients at risk for progression toward definite SSc

Table 1 Proteins of interest in the discovery cohort after bagging validation

Target	Gene	Accuracy^a	P*
NKp30	NCR3	0.835	0.0071
Endostatin	COL18A1	0.835	0.0075
bFGF	FGF2	0.83	0.0075
ECM1	ECM1	0.766	0.0248
FGF 18	FGF18	0.755	0.0324
PHI	GPI	0.749	0.0345
Fibronectin 1.3 (FN1.3)	FN1	0.740	0.0402
Ubiquitin +1	RPS27A	0.740	0.0402
PAF AHβ subunit (PABF)	PAFAH1B2	0.734	0.0459
FABP	FABP1	0.732	0.0467

*Family-wise corrected p values of bagging accuracy after 10,000 permutations
^aAverage accuracy to predict evolution after 100 resampling with replacement (bagging accuracy)

ISSN: 1478-6362