Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA+ individuals without a systemic autoimmune rheumatic disease diagnosis

Table 2 Correlations between cytokines for all subjects

Cytokine	With cytokine	Correlation	95% CI		p value
IFN5	CXCL-10	0.12378	0.001679	0.241790	0.0466
IFN5	Galectin-9	0.29788	0.182062	0.404577	<0.0001
IFN5	IFN-α by ELISA	0.54516	0.454252	0.623581	<0.0001
IFN5	IFN-α by Simoa	0.70824	0.640511	0.763888	<0.0001
IFN5	IFN-γ	0.12436	0.002743	0.241896	0.0447
CXCL-10	Galectin-9	0.74356	0.683753	0.792397	<0.0001
CXCL-10	IFN-α by ELISA	0.18992	0.070689	0.303147	0.0019
CXCL-10	IFN-α by Simoa	0.15592	0.033657	0.273010	0.0125
CXCL-10	IFN-γ	0.28330	0.167120	0.390802	<0.0001
Galectin-9	IFN-α by ELISA	0.30807	0.194242	0.412745	<0.0001
Galectin-9	IFN-α by Simoa	0.23755	0.117934	0.349549	0.0001
Galectin-9	IFN-γ	0.27885	0.162421	0.386702	<0.0001
IFN-α by ELISA	IFN-α by Simoa	0.59586	0.510414	0.668379	<0.0001
IFN-α by ELISA	IFN-γ	0.09315	−0.027377	0.210669	0.1290
IFN-α by Simoa	IFN-γ	0.04034	−0.082748	0.162064	0.5209

Spearman’s correlation coefficient for the association between the indicated cytokines, together with the 95% confidence interval (CI). Significant p values are bolded

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