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Table 1 Common genes identified by TWAS in conjunction with mRNA expression profiles

From: Identification of candidate genes and pathways associated with juvenile idiopathic arthritis by integrative transcriptome-wide association studies and mRNA expression profiles

Gene

Chr

BEST.GWAS.ID

TWAS.Z

TWAS.P

adj.P

logFC

ANXA3

4

rs1154761

2.08

3.78 × 10−2

1.00 × 10−5

1.94

GPR146

7

rs10246200

2.00

4.59 × 10−2

1.00 × 10−5

1.36

ANKRD9

14

rs2298877

− 2.02

4.32 × 10−2

2.00 × 10−5

1.26

TMEM158

3

rs7622843

2.22

2.66 × 10−2

< 1.00 × 10−5

1.24

  1. CHR chromosome, BEST.GWAS.ID rsID of the most significant GWAS SNP in locus, TWAS.Z TWAS Z-score, TWAS.P TWAS P value, adj.P mRNA P value after FDR adjust
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Arthritis Research & Therapy

ISSN: 1478-6362

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