Skip to main content

Table 3 The association between levothyroxine use and risk of KOA radiographic and symptomatic incidence

From: Levothyroxine use and longitudinal changes in thigh muscles in at-risk participants for knee osteoarthritis: preliminary analysis from Osteoarthritis Initiative cohort

Outcomes

Hazard ratio (95%CI), P

KOA radiographic incidence

1.78 (1.15–2.75), P: 0.009*

KOA symptomatic incidence

1.93 (1.19–3.13), P: 0.007*

  1. Cox proportional hazard model was used for analysis. Levothyroxine use, as the independent variable, was associated with an increased risk of KOA incidence over the 8-year follow-up period
  2. CI confidence interval, JSN joint space narrowing, KOA knee osteoarthritis
  3. *P values that remained significant after FDR correction, indicative of significant values