Table 1 Weighted demographic characteristics of all participants

SII

6.181 (0.005)

5.507 (0.004)

5.994 (0.001)

6.316 (0.001)

6.806 (0.004)

< 0.0001

Gender

< 0.0001

 Male

19,523 (51.917)

5399 (57.462)

5001 (53.229)

4703 (50.380)

4420 (44.756)

 Female

18,081 (48.083)

4015 (42.538)

4391 (46.771)

4691 (49.620)

4984 (55.244)

Age

< 0.0001

 Below 60

27,516 (73.173)

6892 (82.354)

6949 (82.953)

7032 (82.786)

6643 (80.032)

 Over 60

10,088 (26.827)

2522 (17.646)

2443 (17.047)

2362 (17.214)

2761 (19.968)

Race

< 0.0001

 White

15,436 (41.049)

2842 (56.742)

3777 (65.819)

4222 (68.871)

4595 (71.053)

 Black

7901 (21.011)

3177 (19.964)

1845 (10.402)

1497 ( 8.327)

1382 ( 7.603)

 Mexican American

7178 (19.088)

1497 (8.905)

1860 (9.461)

1948 (9.664)

1873 (9.001)

 Other

7089 (18.852)

1898 (14.389)

1910 (14.318)

1727 (13.138)

1554 (12.344)

Edu

< 0.0001

 Under high school

9920 (26.414)

2506 (17.438)

2468 (16.382)

2460 (16.301)

2486 (16.818)

 High school or equivalent

8561 (22.795)

2063 (22.092)

2048 (22.397)

2177 (24.450)

2273 (25.640)

 College graduate or above

19,075 (50.791)

4833 (60.469)

4865 (61.221)

4744 (59.249)

4633 (57.542)

PIR

0.055

 Below 1.3

10,545 (30.684)

2659 (21.958)

2571 (20.555)

2602 (20.699)

2713 (22.376)

 1.3–3.5

13,049 (37.97)

3261 (35.950)

3247 (35.517)

3237 (35.238)

3304 (36.065)

 Over 3.5

10,773 (31.347)

2631 (42.091)

2767 (43.928)

2761 (44.064)

2614 (41.560)

BMI

< 0.0001

 Below 25

11,841 (31.975)

3218 (37.163)

2977 (34.391)

2766 (30.822)

2880 (32.605)

 25–30

12,783 (34.519)

3316 (34.919)

3298 (35.603)

3244 (34.543)

2925 (31.384)

 Over 30

12,408 (33.506)

2772 (27.918)

3013 (30.006)

3243 (34.635)

3380 (36.010)

Hypertension

< 0.0001

 No

23,543 (62.608)

6017 (69.978)

6052 (70.143)

5923 (67.733)

5551 (64.058)

 Yes

14,061 (37.392)

3397 (30.022)

3340 (29.857)

3471 (32.267)

3853 (35.942)

Diabetes

< 0.0001

 No

29,412 (78.215)

7459 (83.957)

7362 (83.934)

7433 (83.852)

7158 (81.057)

 Pre-diabetes

2523 (6.709)

596 (6.101)

627 (6.013)

639 (6.282)

661 (6.713)

 Diabetes

5669 (15.076)

1359 ( 9.942)

1403 (10.052)

1322 ( 9.866)

1585 (12.230)

Hyperlipidemia

< 0.0001

 No

11,672 (31.039)

3321 (37.126)

2899 (32.367)

2688 (29.487)

2764 (30.289)

 Yes

25,932 (68.961)

6093 (62.874)

6493 (67.633)

6706 (70.513)

6640 (69.711)

Alcohol use

< 0.0001

 Never

4805 (14.232)

1241 (12.196)

1217 (11.216)

1147 (10.663)

1200 (11.052)

 Former

5315 (15.743)

1282 (11.817)

1246 (11.648)

1313 (13.312)

1474 (14.559)

 Mild

10,961 (32.465)

2905 (36.822)

2774 (36.178)

2711 (34.791)

2571 (31.805)

 Moderate

5191 (15.375)

1256 (17.608)

1332 (17.717)

1319 (17.393)

1284 (17.206)

 Heavy

7490 (22.185)

1691 (21.557)

1836 (23.241)

1982 (23.841)

1981 (25.377)

Smoke

< 0.0001

 Never

21,053 (56.031)

5508 (57.649)

5391 (57.413)

5271 (55.789)

4883 (51.418)

 Former

8346 (22.212)

2023 (22.562)

2081 (22.149)

2010 (21.402)

2232 (23.299)

 Now

8175 (21.757)

1874 (19.789)

1912 (20.439)

2108 (22.809)

2281 (25.283)

Work activity

0.006

 No

19,774 (52.595)

5159 (48.399)

4875 (45.917)

4831 (44.956)

4909 (46.196)

 Yes

17,823 (47.405)

4255 (51.601)

4513 (54.083)

4563 (55.044)

4492 (53.804)

Arthritis

< 0.0001

 No

34,962 (92.974)

8806 (94.972)

8803 (95.222)

8780 (95.295)

8573 (93.514)

 Yes

2642 (7.026)

608 (5.028)

589 (4.778)

614 (4.705)

831 (6.486)

White blood cell

7.235 (0.025)

6.139 (0.039)

6.750 (0.025)

7.357 (0.029)

8.526 (0.035)

< 0.0001

Red blood cell

4.736 (0.006)

4.717 (0.008)

4.747 (0.009)

4.755 (0.007)

4.724 (0.009)

< 0.0001

Lymphocyte

2.151 (0.009)

2.456 (0.026)

2.220 (0.010)

2.094 (0.010)

1.877 (0.009)

< 0.0001

Neutrophils

4.281 (0.018)

2.932 (0.015)

3.747 (0.015)

4.448 (0.018)

5.791 (0.027)

< 0.0001

Platelet

254.407 (0.655)

209.898 (0.780)

240.372 (0.796)

263.130 (0.816)

297.571 (1.011)

< 0.0001