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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Site-specific assessment of spinal radiographic progression improves detection of TNF blocker-associated disease modification in axial spondyloarthritis: longitudinal observational data from the Swiss Clinical Quality Management Registry

Fig. 2

Multivariable analysis of 616 radiographic intervals from 432 patients for the identification of factors associated with spinal radiographic progression in the cervical spine (blue) and the lumbar spine (green). Progression was defined as A an increase in ≥ 1 mSASSS unit per spinal segment in 2 years and B as the formation of at least one new syndesmophyte per spinal segment in 2 years. BMI, body mass index; HLA-B27, human leucocyte antigen B27; mSASSS, modified Stoke Ankylosing Spondylitis Spinal Score; NSAIDs, nonsteroidal anti-inflammatory drugs; Ref, reference; TNFi, tumour necrosis factor inhibitor. Asterisk symbol (*) indicates the following: mSASSS at start of each 2-year radiographic interval in A and presence of syndesmophytes at start of each 2-year radiographic interval (yes vs no) in B

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