Fig. 4
From: Cutaneous lesions in psoriatic arthritis are enriched in chemokine transcriptomic pathways
ACKR2 is upregulated in PsA skin lesions with overexpression in the suprabasal epidermis. Relative ACKR2 mRNA expression normalised to TATA-binding protein in full-thickness skin biopsies from a patients with PsA and healthy controls and b in paired samples of uninvolved and lesional skin from participants with PsA. Skin samples were probed for ACKR2 by RNAScope and detected with Red detection agent. c HC, d PsA uninvolved and e–f PsA lesional skin. ACKR2-positive cells stain red. Scale bars 50 μm. *** p 0.0006, **** p < 0.0001