Table 1 The 25 most downregulated genes in PsA lesional skin compared with healthy control skin

LINC02169

Long intergenic non-protein coding RNA 2169

 − 8.5

3.87E − 11

DGAT2L6

Diacylglycerol O-acyltransferase 2 like 6

 − 7.75

2.75E − 12

MOGAT1

Monoacylglycerol O-acyltransferase 1

 − 7.72

2.41E − 08

IL12A-AS1

IL12A antisense RNA 1

 − 7.67

1.21E − 06

AADACL3

Arylacetamide deacetylase like 3

 − 7.62

4.01E − 13

AC112243.1

NA

 − 7.51

6.28E − 10

AGR3

Anterior gradient 3, protein disulphide isomerase family member

 − 7.22

1.33E − 16

AL513321.2

NA

 − 7.21

2.4E − 18

GAL

Galanin and GMAP prepropeptide

 − 7.12

1.93E − 12

AC138647.1

NA

 − 7

8.25E − 15

AWAT2

Acyl-CoA wax alcohol acyltransferase 2

 − 6.98

1.37E − 11

C1ORF158

Chromosome 1 open reading frame 158

 − 6.93

8.08E − 05

LINC02527

Long intergenic non-protein coding RNA 2527

 − 6.8

4.07E − 15

AC022784.6

NA

 − 6.65

4.97E − 17

THRSP

Thyroid hormone responsive

 − 6.64

2.37E − 13

AC109462.2

NA (cluster0007)^a

 − 6.57

7.31E − 06

PM20D1

Peptidase M20 domain containing 1

 − 6.55

6.44E − 12

HSD3BP2

Hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 2

 − 6.5

1.18E − 05

AWAT1

Acyl-CoA wax alcohol acyltransferase 1

 − 6.45

2.05E − 08

AL158817.1

NA (cluster0007)^a

 − 6.38

7.5E − 05

TRIM55

Tripartite motif-containing 55

 − 6.34

6.65E − 09

AC110009.1

NA (cluster0007)^a

 − 6.2

1.07E − 05

AC091163.1

NA (cluster0007)^a

 − 6.05

4.65E − 06

AP001330.1

NA

 − 6.04

2.64E − 15

ZNF725P

Zinc finger protein 725, pseudogene

 − 5.95

3.65E − 05