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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Osteoarthritis genetic risk acting on the galactosyltransferase gene COLGALT2 has opposing functional effects in articulating joint tissues

Fig. 4

Investigation of enhancer activity at the DMR region in SW982 synovial cells. A Lucia reporter assays assessing the enhancer activity in the presence of constructs containing the 3 haplotypes of rs943409 and rs734657 and B the 3 haplotypes in a methylated or unmethylated state; values were normalised to those in an empty vector control. Symbols represent individual samples (n = 5 per group). Bars show the mean ± SEM. *P < 0.05; **P < 0.01, calculated by paired t-test with Holm-Šídák correction for empty control versus construct or by unpaired t-test with Holm-Šídák correction for unmethylated construct versus methylated construct

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Arthritis Research & Therapy

ISSN: 1478-6362

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