Fig. 2
From: Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis
Cellular expression of LAG-3 in PBMCs and SFMCs. A Cellular expression of LAG-3 on CD3 + CD4 + T cells from PBMCs and SFMCs in HC (n = 6) and cRA (n = 9). B Representative FACS data from one of the cRA patients shown in the flow plot. C Distribution of LAG-3 + cells in relation to CD45R0 presented in the bar graph (n = 12) and representative FACS data from one of the cRA patients shown in the flow plot (D). E Percentages of LAG-3 + cells determined by PD-1 co-expression are presented in the bar graph (n = 4) and representative FACS data from one of the cRA patients are shown in the flow plot (F). G Percentages of LAG-3 + cells capable of IL-2 production or not (n = 4) with a representative flow plot in H. Bars indicate the median and whiskers standard deviation. The level of significance is indicated on the graph. Differences were analyzed using the paired t tests or Mann–Whitney test to compare the two groups