Fig. 3

Receiver operating characteristic curves for identifying patients with knee OA using PRSs and clinical data. Line plot showing receiver operating characteristic curves of PRSs and models, including clinical data. MODEL I integrated risk models using clinical data, including sex, age, and BMI; MODEL II integrated risk models using clinical data, including sex, age, and BMI, and MTAG-based multi-population knee OA PRS. OA, osteoarthritis; PRS, polygenic risk score; BMI, body mass index; MTAG, multi-trait analysis of genome-wide association