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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis

Fig. 3

Knockdown of TUG1 inhibits chondrocyte viability and promotes chondrocyte apoptosis and inflammation. A qRT-PCR assay of TUG1 expression after interference using siRNA. B CCK-8 assay of Si-TUG1 for cellular value-added viability. C Immunofluorescence detection of collagen II and MMP13 protein expression of Si-TUG1. D Western blotting to detect the protein expression of collagen II, MMP13, Bax, Bcl2, and cleaved-caspase3 in Si-TUG1. E Flow cytometry detection of apoptosis in Si-TUG1. All data are shown as SEM ± mean based on 3 independent experiments. *P < 0.05; **P < 0.01; P < 0.001

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Arthritis Research & Therapy

ISSN: 1478-6362

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