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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis

Fig. 7

Overexpression of DUSP1 attenuates chondrocyte apoptosis and extracellular matrix degradation. A Differential analysis of datasets from the GEO database (GSE75181, GSE114007) using the limma package and taking intersections of differential genes. B KEGG enrichment analysis of the differential genes. C PPI analysis of the differential genes. D qRT-PCR to detect the mRNA expression level of DUSP1 after transfection with AD-DUSP1. E Western blotting to detect protein expression of DUSP1, collagen II, MMP13, Bax, Bcl2, and cleaved-caspase3 after transfection with AD-DUSP1. All data are shown as SEM ± mean based on 3 independent experiments. *P < 0.05; **P < 0.01; P < 0.001

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Arthritis Research & Therapy

ISSN: 1478-6362

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