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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil

Fig. 1

Predicted frequency of immune cell types in whole blood. A Principal component (PC) plot of PC1 and PC2 for all patient samples. B Relative frequency of each of the 22 cell types predicted using CIBERSORTx in each sample. C The predicted frequency of the 11 selected cell types in the whole cohort. D Correlation matrix of the 11 cell types in the whole cohort. Spearman r coefficients are shown and the intensity of the colour indicates the strength of the correlation. E Pseudoheatmap of the 11 cell types according to exposure to GC, HCQ and immunosuppressants. The colour shows the magnitude of the Z score, *p < 0.05. HCQ, hydroxychloroquine; GC, glucocorticoids; AZA, azathioprine; MTX, methotrexate; MMF, mycophenolate mofetil; CYC, cyclophosphamide

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Arthritis Research & Therapy

ISSN: 1478-6362

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