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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil

Fig. 4

Predicted gene expression in CD4 + T cells in patients exposed to MMF. A Volcano plot of DEGs predicted in the CD4 T cell subset according to exposure to MMF. Horizontal line shows -log10 adjusted p value and vertical line shows log2 fold change. B GO analysis of over-represented biological pathways in the 157 DEGs with adjusted p < 0.05 between patients exposed or not to MMF. C Heatmap of genes in CD4 T cells with hierarchical clustering of samples (horizontal) and genes (vertical). The vertical bars show the top GO biological process for each cluster of genes

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