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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Deubiquitinase USP16 induces gouty arthritis via Drp1-dependent mitochondrial fission and NLRP3 inflammasome activation

Fig. 5

Deubiquitination and stabilization of Drp1 by USP16. A The protein levels of USP16 and Drp1 in macrophages were detected by western blot. B The protein stability of Drp1 was examined by western blot in the presence of CHX. C The ubiquitination of Drp1 was assessed by Co-IP. GAPDH acted as an internal control. *, P < 0.05, **, P < 0.01, ***, P < 0.001

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Arthritis Research & Therapy

ISSN: 1478-6362

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