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Table 3 Comparison of medications between patients with MDA5+DM in the survival and non-survival groups

From: Mortality risk in patients with anti-MDA5 dermatomyositis is related to rapidly progressive interstitial lung disease and anti-Ro52 antibody

 

Non-survival group (N = 32)

Survival group (N = 94)

P-value

Glucocorticoids only

12 (37.5)

16 (17.0)

0.016

Dual therapy

16 (50.0)

58 (61.7)

0.245

 Glucocorticoids + tacrolimus

5 (15.6)

31 (33.0)

0.061

 Glucocorticoids + intravenous cyclophosphamide

7 (21.9)

24 (25.5)

0.678

 Glucocorticoids + mycophenolate mofetil

1 (3.1)

1 (1.1)

1.000

 Glucocorticoids + cyclosporine A

2 (5.9)

2 (2.1)

0.615

 Glucocorticoids + thalidomide

1 (3.1)

0 (0)

0.254

Triple therapy

4 (12.5)

20 (21.3)

0.275

Intravenous pulse methylprednisolone

7 (21.9)

6 (6.4)

0.013

Rituximab

2 (6.3)

1 (1.1)

0.322

Tocilizumab

2 (6.3)

1 (1.1)

0.322

Tofacitinib

0 (0)

9 (9.6)

0.110

Intravenous immunoglobulin

21 (65.5)

40 (42.6)

0.024

  1. Data presented as number and percentage. Pulse methylprednisolone includes treatment with glucocorticoids alone or glucocorticoids with other immunosuppressants. Triple therapy includes high-dose glucocorticoids, tacrolimus, and intravenous cyclophosphamide. Bold text highlights the significance
  2. MDA5+DM, anti-MDA5 dermatomyositis