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Table 1 Ultrasound and histological data

From: The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis

Biopsy code, n°

GS score

PD score

Fragments H&E, n total/IST (TQR)

Biopsy gradablea

Krenn score (synovitis grade)

Vascularity score

Cell aggregation G2/G3 (LAI)

1

3

2

12/9 (75%)

 + 

6.5 (high)

1

 + / + (0.89)

2

2

2

16/0 (0%)

 − 

ne (ne)

ne

ne (ne)

3

2

2

21/14 (67%)

 + 

3 (low)

0.5

 + / + (0.14)

4

2

3

14/14 (100%)

 + 

6 (high)

1.5

 + / + (0.86)

5

2

1

23/22 (96%)

 + 

5.5 (high)

0

 + / − (0.14)

6

1

2

16/5 (31%)

 + 

4 (low)

0.5

 − / − (0.00)

7

3

3

13/12 (92%)

 + 

4.5 (low)

1

 + / − (0.33)

8

2

3

19/9 (47%)

 + 

4.5 (low)

0.5

 + / − (0.22)

9

3

2

12/12 (100%)

 + 

7.5 (high)

2

 + / + (0.50)

10

3

3

20/9 (45%)

 + 

4.5 (low)

1

 − / − (0.00)

11

1

3

9/7 (78%)

 + 

5 (high)

0.5

 + / − (0.37)

12

2

2

10/8 (80%)

 + 

5 (high)

1.5

 + / + (0.62)

13

2

1

17/6 (35%)

 + 

3.5 (low)

0.5

 − / − (0.00)

14

2

2

24/18 (75%)

 + 

5.5 (high)

2

 + / − (0.18)

15

3

2

19/10 (53%)

 + 

4 (low)

0

 − / − (0.00)

16

2

3

20/20 (100%)

 + 

6 (high)

1.5

 + / + (0.87)

17

2

3

18/16 (89%)

 + 

4.5 (low)

1

 + / + (0.59)

18

3

3

18/18 (100%)

 + 

6.5 (high)

2.5

 + / + (0.52)

19

3

2

16/12 (75%)

 + 

5.5 (high)

1.5

 + / − (0.23)

20

2

1

18/13 (72%)

 + 

4.5 (low)

0.5

 + / − (0.16)

  1. GS gray scale of the biopsied wrist, PD power Doppler of the biopsied wrist, Fragments H&E fragments selected for histopathology, IST intact synovial tissue, TQR tissue quality ratio, G2/G3 grade 2/grade 3 cell aggregates, LAI lymphocyte aggregation index, ne not evaluable
  2. aCharacterized by a visible lining layer and ≥ 4 fragments displaying IST