Serum IL-23 significantly decreased in obese patients with psoriatic arthritis six months after a structured weight loss intervention

Table 3 Spearman correlations for cytokines, adipokines, disease activity measurements and BMI between baseline (BL) and 6 months (M6) of follow-up in patients with psoriatic arthritis (PsA), n = 41

	ΔBMI	p-value	ΔDAS28CRP	p-value	ΔDAPSA	p-value	ΔCRP	p-value
ΔBMI			0.450	0.003	0.178	0.264	0.336	0.032
∆TNF-α	0.342	0.028	0.303	0.054	0.272	0.085	0.144	0.371
∆IL-1β	0.263	0.184	0.234	0.241	0.220	0.271	0.056	0.781
∆IL-6	0.082	0.610	0.115	0.474	0.161	0.316	0.249	0.116
∆IL-8	-0.140	0.382	-0.094	0.559	-0.094	0.561	-0.134	0.404
∆IL-12/IL-23 p40	0.294	0.087	0.260	0.132	0.307	0.073	-0.044	0.802
∆IL-13	0.401	0.010	0.232	0.150	0.257	0.110	-0.174	0.284
∆IL-17	0.530	0.042	0.448	0.094	0.209	0.454	0.204	0.466
∆IL-23	0.671	< 0.001	0.460	0.005	0.223	0.198	0.460	0.005
∆IFN-γ	0.271	0.086	0.253	0.111	0.256	0.106	-0.050	0.755
∆Resistin	0.034	0.831	0.064	0.691	-0.005	0.975	0.089	0.579
∆Leptin	0.554	< 0.001	0.368	0.019	0.315	0.048	0.260	0.105
∆HMW adiponectin	-0.251	0.113	-0.113	0.481	-0.048	0.767	-0.396	0.010
∆Tot-adiponectin	-0.318	0.043	-0.189	0.237	-0.159	0.320	-0.158	0.324

∆ = difference between BL and M6
Spearman correlations between BL and M6
BMI body mass index, CRP c-reactive protein, DAS28CRP disease activity score, DAPSA disease activity in psoriatic arthritis, HMW high molecular weight, IFN interferon, IL interleukin, TNF tumor necrosis factor, Tot total

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