Fig. 1

IGU suppresses Tfh cells in pSS patients. Flowcytometry analysis of (A) CD4⁺CXCR5⁺PD-1⁺, (B) CD4⁺CXCR5⁺ICOS⁺, (C) CD4⁺IL-21⁺, (D) CD4⁺CXCR5⁺PD-1⁺ICOS⁺ follicular T helper (Tfh) cells, (E) CD27⁺IgD⁻switched memory B cells, (F) CD38^hiCD27^hi plasmablasts, and (G) CD38^hiCD138⁺ plasma cells isolated from peripheral blood of pSS patients (n = 13). Data were presented as mean ± SD. Data were obtained from independent experiments. *p < 0.05, **p < 0.01 by ANOVA