Fig. 3

Lymphocytes in advanced OA synovium. A,B Relative frequency (%) of T cells (CD3+) and B cells (CD19+) as a percentage of lymphocytes. C Relative frequency of T cell subsets, including CCR6+, CD8+, GDTCR+, and CD161+ T cells. D-G Relationship between the relative frequency (%) of CCR6+ T cells and age in years (D), body mass index (E), and mean compartmental Kellgren-Lawrence (KL) grade (F). n=10 (H) Representative immunofluorescence staining of CD3 (cyan), CD8 (yellow), CD19 (pink) in advanced OA synovium; DAPI staining (blue) was used to visualise nuclei and CD146 (orange) to visualise vessels