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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Transgenic disruption of endogenous glucocorticoid signaling in osteoblasts does not alter long-term K/BxN serum transfer-induced arthritis

Fig. 1

Study design and group distributions according to genotype and arthritis protocol. K/BxN STIA was induced by i.p. injections on days 0 and 2 in WT STIA and tg STIA mice (top row) and boosted with additional i.p. injections on days 14 and 28 in WT STIA boost and tg STIA boost animals to maintain a chronic state of arthritis (middle row). CTRL mice were injected with PBS respectively at the same time points (bottom row). As there was no clinical difference between CTRL animals that were injected on days 0 and 2 and those injected on days 0, 2, 14, and 28, CTRL animals were grouped according to their genotype. CTRL, control; i.p., intraperitoneal; PBS, phosphate-buffered saline; STIA, serum transfer-induced arthritis; tg, transgenic; WT, wild type

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Arthritis Research & Therapy

ISSN: 1478-6362

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