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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Causal relationship between PCSK9 inhibitor and autoimmune diseases: a drug target Mendelian randomization study

Fig. 2

The effect of PCSK9 and HMGCR inhibitor on coronary heart disease and autoimmune diseases. Asterisk (*) represents the linkage disequilibrium (LD) parameter in the selection of instrumental variables changes from r2 < 0.3 to r2 < 0.1. NSNP, number of single nucleotide polymorphisms; OR, odds ratio; CI, confidence interval; PCSK9, proprotein convertase subtilisin/kexin 9; HMGCR, 3-hydroxy-3-methylglutaryl coenzyme A reductase; CHD, coronary heart disease; SLE, systemic lupus erythematosus; RA, rheumatoid arthritis; MG, myasthenia gravis; MS, multiple sclerosis; CD, Crohn’s disease; UC, ulcerative colitis; T1D, type 1 diabetes

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Arthritis Research & Therapy

ISSN: 1478-6362

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