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Table 3 The autoantibody profile of myositis patients and the distribution of HFA-PEFF score tertiles in each subgroup

From: Value of the HFA-PEFF diagnostic algorithms for heart failure with preserved ejection fraction to the inflammatory myopathy population

HFA-PEFF score tertiles

Low

Intermediate

High

p-value

Myositis-specific antibodies (MSAs), n (%)

 Anti-MDA5

18(32.7%)

29(52.7%)

8(14.5%)

0.335

 Anti-Jo1

17(38.6%)

24(54.5%)

3(6.8%)

 Anti-EJ

5(31.3%)

8(50.0%)

3(18.8%)

 Anti-PL7

7(33.3%)

10(47.6%)

4(19.0%)

 Anti-PL12

5(38.5%)

6(46.2%)

2(15.4%)

 Anti-SRP

5(23.8%)

8(38.1%)

8(38.1%)

 Anti-HMGCR

5(55.6%)

2(22.2%)

2(22.2%)

 Anti-TIF1γ

2(22.2%)

4(44.4%)

3(33.3%)

 Anti-Mi2

2(33.3%)

3(50.0%)

1(16.7%)

 Anti-NXP2

1(33.3%)

2(66.7%)

0(0.0%)

 Anti-SAE

1(25.0%)

3(75.0%)

0(0.0%)

 MSA negative

11(57.9%)

8(42.1%)

0(0.0%)

 

Myositis-associated antibodies (MAAs), n (%)

 Anti-Ku

3(33.3%)

5(55.6%)

1(11.1%)

0.894

 Anti-PMScl75/100

8(36.4%)

11(50.0%)

3(13.6%)

0.969

 AMA-M2

2(11.1%)

10(55.6%)

6(33.3%)

0.011

 Anti-Ro52

37(30.3%)

67(54.9%)

18(14.8%)

0.096

  1. HFA-PEFF Heart Failure Association Pre-test assessment, Echocardiography and natriuretic peptide, Functional testing, Final etiology