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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice

Fig. 5

Tau deletion inhibits macrophage infiltration and M1 polarization in CIA. A Representative images of immunohistochemical staining of F4/80, iNOS and CD206 in the synovium of ankle joints from WT and Tau-/- mice with or without CIA. Scale bar: 100 µm. B-D Quantification of F4/80 positive (B), iNos positive (C) and CD206 positive (D) macrophages in the synovium of ankle joints from WT and Tau-/- mice with or without CIA. n = 6 mice for each group. ****p < 0.0001

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